BBC interview on national lockdown and mandatory vaccination

On 22 November 2021, Austria went into a full national lockdown for 20 days to help curb SARS-CoV-2 infection numbers. On the programme, Peter Willeit provides an epidemiological perspective on the lockdown and on vaccination against SARS-CoV-2 being mandatory from February 2022. With permissions from the BBC.

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Towards a European strategy to address the COVID-19 pandemic

How should Europe deal with the COVID-19 pandemic in the future? Which strategies should be pursued and what specific risks should be considered? In September 2021, we published a call in the Lancet for closer European collaboration in addressing the COVID-19 pandemic. Together with this call in the Lancet, we published an expert opinion paper […]

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Sensitivity and specificity of antigen-based self-testing in Austrian schools

This study evaluates the performance of the antigen based anterior nasal screening programme that was used at Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1 to 8) with an RT-qPCR-based prospective cohort study comprising a representative sample of 244 schools. Considering a […]

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Prevalence of RT-PCR-detected SARS-CoV-2 infection at schools: First results from the Austrian School-SARS-CoV-2 Study

There is much debate about the role of schools and children in the SARS-CoV-2 pandemic. In a consortium of four Austrian universities (Medical University of Innsbruck, Medical University of Graz, Medical Faculty of the JKU Linz, University of Vienna), we set out to reliably quantify the prevalence of SARS-CoV-2 infections at schools detected with reverse-transcription […]

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Design and rationale of the Proof-ATHERO consortium

This paper – published in Gerontology – outlines the broad aims of the Proof-ATHERO consortium and describes the principal methodology of data management and analysis of study data. The Proof-ATHERO consortium collates individual-participant data of studies with information on atherosclerosis measures, risk factors for cardiovascular disease, and incident cardiovascular events. More details about the consortium […]

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Carotid intima-media thickness progression as surrogate marker for cardiovascular risk

In this paper – published in Circulation – we quantified the association between the intervention effects on carotid intima media thickness (cIMT) progression and the intervention effect on cardiovascular risk. Therefore, we systematically reviewed the literature and collected aggregated literature based data and individual participant data from 119 randomised controlled trials involving a total of […]

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Which body mass index is associated with the greatest survival?

Overweight and obesity are increasing worldwide. To help assess their relevance to mortality in different populations we meta-analysed prospective studies of body-mass index, limiting confounding and reverse causality by restricting analyses to never-smokers and excluding pre-existing disease and the first 5 years of follow-up. Of 10 625 411 participants in Asia, Australia and New Zealand, Europe, and […]

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Reductions in life expectancy with cardiometabolic disease

Cardiometabolic diseases often occur in one and the same individual. In this paper published in JAMA, we aimed to estimate by how much life expectancy is reduced in individuals suffering from cardiometabolic multimorbidity. In our analysis, we calculated mortality rates and hazard ratios (HRs) adjusted for age and sex using individual participant data from the […]

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Improving cardiovascular disease prediction with lipoprotein(a)

Lipoprotein(a) [Lp(a)] is a causal risk factor for cardiovascular disease. In this paper published in JACC we aimed to investigate whether Lp(a) modifies clinical risk assessment in the general community. We measured Lp(a) in 826 men and women (age range, 45 to 84 years) and recorded incidence of cardiovascular diseases over 15 years of follow-up. […]

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Leukocyte telomere length is linked to cardiovascular risk

Leading on from our work on telomeres in the Bruneck Study, we have conducted in this paper published in the BMJ a systematic review and meta-analysis to assess the association between leucocyte telomere length and cardiovascular risk. Our analysis included studies published up to March 2014 identified through searches of Medline, Web of Science, and […]

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