Design and rationale of the Proof-ATHERO consortium

This paper – published in Gerontology – outlines the broad aims of the Proof-ATHERO consortium and describes the principal methodology of data management and analysis of study data. The Proof-ATHERO consortium collates individual-participant data of studies with information on atherosclerosis measures, risk factors for cardiovascular disease, and incident cardiovascular events. More details about the consortium […]

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Carotid intima-media thickness progression as surrogate marker for cardiovascular risk

In this paper – published in Circulation – we quantified the association between the intervention effects on carotid intima media thickness (cIMT) progression and the intervention effect on cardiovascular risk. Therefore, we systematically reviewed the literature and collected aggregated literature based data and individual participant data from 119 randomised controlled trials involving a total of […]

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