VITAL – Vital Study

Principal contacts

Pythia T. Nieuwkerk - Amsterdam University Medical Centers/ Academic Medical Center, Amsterdam, the Netherlands

Erik Stroes - cademic Medical Center, Amsterdam, the Netherlands

Study design

The Vital Study is a two-arm clinical trial based in Amsterdam, the Netherlands. The principal aim of the trial was to investigate the effect of routine care (measuring body weight and blood pressure and performing a capillary lipid profile) versus extended care (routine care plus multifactorial risk-factor counseling, during which the nurse practitioner explained the presence of unmodifiable risk factors, such as age, gender, and family history, and modifiable risk factors, such as lipid levels, diabetes mellitus, blood pressure, overweight, smoking habits, and physical activity) on cardiovascular events. Individuals were selected from the outpatient clinics of the Academic Medical Center and the Slotervaart Hospital in Amsterdam, the Netherlands and were eligible for inclusion if they were aged above 18 years, with indications for statin use. Written informed consent was obtained from each patient, and the institutional review board of the Academic Medical Center approved the study protocol.

 

Key publications

Intervention to Improve Adherence to Lipid-Lowering Medication and Lipid-Levels in Patients With an Increased Cardiovascular Risk. Am J Cardiol. 2012 Sep 1;110(5):666-72