VITAL – Vital Study
Pythia T. Nieuwkerk - Amsterdam UMC- Location AMC, Amsterdam, the Netherlands
Erik Stroes - Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands
The Vital Study is a two-arm clinical trial based in Amsterdam, the Netherlands. The principal aim of the trial was to investigate the effect of routine care (measuring body weight and blood pressure and performing a capillary lipid profile) versus extended care (routine care plus multifactorial risk-factor counseling, during which the nurse practitioner explained the presence of unmodifiable risk factors, such as age, gender, and family history, and modifiable risk factors, such as lipid levels, diabetes mellitus, blood pressure, overweight, smoking habits, and physical activity) on cardiovascular events. Individuals were selected from the outpatient clinics of the Academic Medical Center and the Slotervaart Hospital in Amsterdam, the Netherlands and were eligible for inclusion if they were aged above 18 years, with indications for statin use. Written informed consent was obtained from each patient, and the institutional review board of the Academic Medical Center approved the study protocol.
Intervention to Improve Adherence to Lipid-Lowering Medication and Lipid-Levels in Patients With an Increased Cardiovascular Risk. Am J Cardiol. 2012 Sep 1;110(5):666-72