MG600 – Effects of Magnesium Supplementation on Vascular Structure and Function in Hypertensive Patients Study
Mario F. Neves - State University of Rio de Janeiro, Rio de Janeiro, Brazil
Ana R. Cunha - State University of Rio de Janeiro, Rio de Janeiro, Brazil
The Effects of Magnesium Supplementation on Vascular Structure and Function in Hypertensive Patients Study (MG600) is a two-arm clinical trial based in Rio de Janeiro, Brazil. The principal aim of the trial was to investigate the effect of Magnesium chelate (600mg/day) versus placebo on vascular structure and function in hypertensive women. Individuals were eligible for inclusion if they were aged between 40 and 65 years, with previous diagnosis of essential hypertension, and were on stable monotherapy with hydrochlorothiazide 25mg for the previous four weeks. The protocol was approved by the local ethics committee, and all subjects gave their written informed consent.
Link to study webpage – https://clinicaltrials.gov/ct2/show/NCT01151683
Altered vascular structure and wave reflection in hypertensive women low magnesium levels. J Am Soc Hypertens. 2013 Sep-Oct;7(5):344-52
Oral magnesium supplementation improves endothelial function and attenuates subclinical atherosclerosis in thiazide-treated hypertensive women. J Hypertens. 2017 Jan;35(1):89-97