EGE STUDY – Ege Study

Principal contacts

Gülay Aşçi - Ege Üniversitesi, Bornova-Izmir, Turkey

Ercan Ok - Izmir Bozyaka Education and Research Hospital, Izmir, Turkey

Study design

The Ege Study is a clinical trial with a 2×2 factorial design based at eight haemodialysis centres in Turkey. The principal aim of the trial was to investigate the effect of high- or low-flux dialyzers and ultrapure or standard dialysate on cardiovascular outcomes. Individuals were eligible for inclusion if they were aged between 18 and 80 years and were on thrice weekly haemodialysis. All patients provided written informed consent. The local ethics committee of Ege University approved the study protocol.


Key publications

The impact of membrane permeability and dialysate purity on cardiovascular outcomes. J Am Soc Nephrol. 2013 May;24(6):1014-23

Glycated hemoglobin predicts overall and cardiovascular mortality in non-diabetic hemodialysis patients. Clin Nephrol. 2014 Sep;82(3):173-80