CAPS – Carotid Atherosclerosis Progression Study

Principal contacts

Matthias W. Lorenz - Goethe University, Frankfurt am Main, Germany

Matthias Sitzer - Klinikum Herford, Herford, Germany

Helmuth Steinmetz - Goethe University, Frankfurt am Main, Germany

Study design

The Carotid Atherosclerosis Progression Study (CAPS) is a general population study based in Western Germany. Members of a German primary healthcare scheme were invited and recruited between 1995 and 2000. Individuals were included if they had no history of stroke, transient ischaemic attack, coronary heart disease, or peripheral arterial disease, and no plaque formation in the carotid system. The study was approved by the ethical review committee of the University Hospital of Frankfurt am Main.


Key publications

C-reactive protein and carotid intimal medial thickness in a community population. J Cardiovasc Risk. 2002 Apr;9(2):97-103

Carotid Intima-Media Thickening Indicates a Higher Vascular Risk Across a Wide Age Range Prospective Data From the Carotid Atherosclerosis Progression Study (CAPS). Stroke. 2006 Jan;37(1):87-92

Clinical usefulness of carotid ultrasound to improve stroke risk assessment: ten-year results from the Carotid Atherosclerosis Progression Study (CAPS). Eur J Prev Cardiol. 2013 Oct;20(5):837-43