POPROSTU – Poznań Prospective Study of Type-1 Diabetic Patients
Principal contacts
Dorota A. Zozulińska-Ziółkiewicz - Poznan University of Medical Sciences, Poznan, Poland
Dariusz Naskręt - Poznan University of Medical Sciences, Poznan, Poland
Aleksandra Araszkiewicz - Poznan University of Medical Sciences, Poznan, Poland
Aleksandra Uruska - Poznan University of Medical Sciences, Poznan, Poland
Study design
The Poznań Prospective Study of Type-1 Diabetic Patients (POPROSTU) is focusing on individuals with type 1 diabetes mellitus and is based in Poznan, Poland. Individuals <35 years of age with newly diagnosed type 1 diabetes, that were hospitalized due to diabetic ketoacidosis at the Department of Internal Medicine and Diabetes in Poznan, were enrolled in this study. Exclusion criteria were uncertain type of diabetes mellitus, kidney failure, liver dysfunction, acute inflammatory process, and other concomitant diseases. The principal aim of the study was to investigate the development and progression of chronic complications in individuals with type 1 diabetes mellitus who were treated with intensive insulin therapy. All subjects were informed about the aim of the study and gave their consent. The study was approved by the local Ethical Committee.
Key publications
Knowledge after five-day teaching program in intensive insulin therapy performed at the onset of type 1 diabetes influence the development of late diabetic complications. Diabetes Res Clin Pract. 2008 Jul;81(1):61-7
Higher risk of microvascular complications in smokers with type 1 diabetes despite intensive insulin therapy. Microvasc Res. 2014 Mar;92:79-84
Baseline diabetic knowledge after 5-day teaching program is an independent predictor of subclinical macroangiopathy in patients with type 1 diabetes (Poznan Prospective Study). Adv Med Sci. 2014 Sep;59(2):240-4
Skin autofluorescence is associated with carotid intima-media thickness, diabetic microangiopathy, and long-lasting metabolic control in type 1 diabetic patients. Results from Poznan Prospective Study. Microvasc Res. 2015 Mar;98:62-7