OSACA2 – Osaka Follow-up Study for Carotid Atherosclerosis
Principal contacts
Shuhei Okazaki - Osaka University Graduate School of Medicine, Osaka, Japan
Kazuo Kitagawa - Tokyo Women's Medical University, Tokyo, Japan
Study design
The Osaka Follow-up Study for Carotid Atherosclerosis 2 (OSACA 2) is focusing on individuals with one or more than one cardiovascular risk factor and is based in Osaka, Japan. Individuals attending the department of Neurology and Cerebrovascular Disease at Osaka University Hospital were enrolled in the study. Exclusion criteria were a clinical cardiovascular disease event in the previous three months, carotid endarterectomy, or carotid artery stenting. The principal aim of the study was to investigate the prediction of cardiovascular events in high-risk patients based on carotid intima-media thickness. The study design was approved by the Ethics Committee of Osaka University Graduate School of Medicine. All participants gave written informed consent before entry to the study.
Key publications
Carotid Intima-Media Thickness and Risk of Cardiovascular Events in High-Risk Patients. Cerebrovasc Dis. 2007;24(1):35-42
Association of Inflammatory Markers and Carotid Intima-Media Thickness with the Risk of Cardiovascular Events in High-Risk Patients. Cerebrovasc Dis. 2010;30(2):180-7
Echogenicity of Medium-to-Large Carotid Plaques Predicts Future Vascular Events. Cerebrovasc Dis. 2014;38(5):354-61