Safarova – Study Safarova et al.

Principal contacts

Marat Ezhov - National Medical Research Center of Cardiology, Moscow, Russia

Maya Safarova -National Medical Research Center of Cardiology, Moscow, Russia

Tatyana Balakhonova - National Medical Research Center of Cardiology, Moscow, Russia

Study design

The Study Safarova et al. is a two-arm clinical trial based in Moscow, Russia. The principal aim of the trial was to investigate the effect of Atorvastatin (10-40mg/day) alone versus Atorvastatin (10-40mg/day) and Nicotinic Acid (1500mg/day) on risk factors of atherosclerosis. Men with coronary heart disease verified by angiography and high lipoprotein(a) were eligible for inclusion.

Link to study webpage – https://clinicaltrials.gov/ct2/show/NCT02515747 

 

Key publications

Pleiotropic Effects of Nicotinic Acid Therapy in Men With Coronary Heart Disease and Elevated Lipoprotein(a) Levels. Kardiologiia. 2011;51(5):9-16